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Chromatin Architecture, Transcription and Genomics (CATG) lab​



DESCRIPTION OF LAB RESEARCH WORK

We study the interplay of genetics and epigenetics in modulating chromatin organization and transcriptional reprogramming in development, differentiation and disease.

LAB MEMBERS
 
LEAD PI
Amartya Sanyal
Nanyang ​Assistant Professor, School of Biological Sciences

Email: asanyal@ntu.edu.sg
Phone:(65) 6513 8270​
Office:SBS-05N-22
 
Aravinda K Chavalmane
Research Fellow

Email: aravinda.ckn@ntu.edu.sg
 
Ankur Sharma
PhD student

Email: ankur012@e.ntu.edu.sg
 
Chen Yao
PhD student

Email: ychen047@e.ntu.edu.sg

CURRENT PROJECTS
  1. Epigene​tic regulation of cancer chemoresistance
  2. Hepatocyte gene regulation
  3. Development of computational tools to study genome

PUBLICATIONS
Full list of publications can be found here​
  • Cis and Trans Chromosomal Interactions Define Pericentric Boundaries in the Absence of Conventional Heterochromatin. Sreekumar L, Jaitly P, Chen Y, Thimmappa BC, Sanyal A, Sanyal K. Genetics. May 2019 genetics.302179.2019; https://doi.org/10.1534/genetics.119.302179
  • High-resolution RNA allelotyping along the inactive X chromosome: evidence of RNA polymerase III in regulating chromatin configuration. Hong R, Lin B, Lu X, Lai LT, Chen X, Sanyal A, Ng HH, Zhang K, Zhang LF. Sci Rep. 2017 Apr 3;7:45460.
  • Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Strunk RC, Weiss ST; CAMP Research Group. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1465-1474.
  • Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma. McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, Wise RA, Szefler SJ, Sharma S, Kho AT, Cho MH, Croteau-Chonka DC, Castaldi PJ, Jain G, Sanyal A, Zhan Y, Lajoie BR, Dekker J, Stamatoyannopoulos J, Covar RA, Zeiger RS, Adkinson NF, Williams PV, Kelly HW, Grasemann H, Vonk JM, Koppelman GH, Postma DS, Raby BA, Houston I, Lu Q, Fuhlbrigge AL, Tantisira KG, Silverman EK, Tonascia J, Weiss ST, Strunk RC; CAMP Research Group. N Engl J Med. 2016 May 12;374(19):1842-52.
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